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Multiple Sclerosis Case Study 16

16) Elisabeth Heinrich - aged 53 years from Weingarten

(name and location changed to protect identity)

Background of Mrs. Elisabeth Heinrich: age 53 years, was working as a school teacher for the past 30 years.  She worked continuously without leave during the duration of her career.  During the treatment she agreed to take a 6 months leave after the therapy which was essential to control the progression of MS. 

Duration of DATMS Therapy – July 2006 for 60 days.
Investigation Method - MRI and CSF investigation.
Diagnosis - 2002
Type of MS – Primary progressive.
Body weight - 66 kg , Height- 1,72 meters

She got the diagnosis of MS in the year 2002. But in the year 2000 she was diagnosed as Encephalomyelitis disseminate. In the year 2002 itself she got 3 exacerbation and that leads to considerable deficit in motor activities were her walking distance was reduced to less than 2 km (she was walking more than 20 km before 2000). And other symptoms like severe pain, bladder symptoms, gait disturbances etc.

Medication – On all the 3 exacerbations period she was on high doses of cortisone. Also medications like Copaxone, Neurontin 300 (twice daily, ingredient is Gaba Pentene).
Kentera – Plaster (Wirkstoff oxybutznin), L-Thyroxin 100, Urbasone, and other food supplements.  She is taking L-Thyroxin 100 on advice from her endocrinologist to avoid a pathology process that may lead to disease of the thyroid gland in the future. (Details not available.) 

Symptoms of MS before DATMS

Altered Sensation – tingling sensation in the legs, dissimilar sensation of the left hand.

Gait & Balance – it is documented that when she walks 200-250 meters, she has considerable pain in the legs. The gait was visibly changed from normalcy, with dragging of the left leg involving her hip joint.

Spasticity - Spasticity is present in both the legs, especially the left leg.Stiffness of the knee joint and  ankle joint.

Coordination- mildly affected.

Bladder & bowel problems - she has to wake up in the night 3-4 times, and reported urinary incontinence, she has to interrupt the therapy several times during the initial days of treatment for urination or bowel urgency. Bowel control was also affected as she says that – flatulence (elimination of gas) without control; frequent constipation.

Cognitive & emotional disturbance- See ‘General’

Mental  - mentally disturbed with mood swings due to MS.

Weakness & fatigue – Fatigued in the afternoon, during warm days and in summer.

Pain - She had severe pain in the legs for which she was taking Gaba pentene 600 mg and still the pain was strong, occasional headache.

Family – no family history of MS or other neurological diseases.

General – As she was having severe side effects from the medication she was taking, she requested that the doses be minimized, especially the Gaba Pentene, which was taken for palliating the pain and was periodically increased to 600 mg still the pain was strong. It is stated that this medicine is not supposed to be taken not longer than 6 months (she had already been taking Gaba Pentene for 4 years). Her condition improved during the first days of treatment ,especiallythe pain and she tried to taper the intake of Gaba pentene , but on the following days she had severe panic attacks, depression and sleeplessness (only 2 –3 hours of sleep during the night) as the withdrawal symptom of Gaba Pentene. On consultation with  the Neurologist who suggested for her to continue taking Gaba Pentene.  However, with her determination and the effect of the DATMS treatment she had slowly tapered the dosage of the drug to 100mg from 600mg. During the treatment, the complication of the Gaba Pentene was disrupting her sleep, where sleep is very essential for the recovery of the patient therefore she had been advised to postpone the treatment for about a month until her sleep was normalized. Earlier in her life she had thyroid surgery and from then onwards she was taking L-thyroxin 100mg, this might have also complicated the situation.

After the DATMS Therapy

Gait & Balance – She is able to walk 600-650 meters and during the second to the last day of the treatment she walked 1000 meters with out having pain or other discomfort.  Moreover the gait style improved considerably in the initial phase of walking (up to 100 meters) and there is no visible disturbance in walking and balance. The dragging of the left leg and hip has visibly improved.

Spasticity - The spasticity of both legs has improved; especially the left leg which was more affected.

Bladder & bowel problems – there was noticeable improvement in the bladder control as she is waking up only 1 time in the night. Even though she had withdrawn for the Kentera-Plaster what was applied for bladder control. The problems of bowel urgency and flatulence without control were absent during the later days of treatment. 

Cognitive & emotional disturbance – she is calm and stable now.

Pain – Pain in the legs were absent during the last phase of treatment. The intensity of the headache is reduced.

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